MEKTOVI

This brand name is authorized in Austria, Australia, Estonia, Spain, Finland, France, Croatia, Ireland, Israel, Italy, Japan, Lithuania, Netherlands, Poland, Romania, United Kingdom, United States

Active ingredients

The drug MEKTOVI contains one active pharmaceutical ingredient (API):

1 Binimetinib UNII 181R97MR71 - BINIMETINIB

Binimetinib is an ATP-uncompetitive, reversible inhibitor of the kinase activity of mitogen-activated extracellular signal regulated kinase 1 (MEK1) and MEK2. Binimetinib inhibits activation of MEK by BRAF and inhibits MEK kinase activity. Binimetinib inhibits growth of BRAF V600 mutant melanoma cell lines. Read about Binimetinib

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
MEKTOVI Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01EE03		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EE Mitogen-activated protein kinase (MEK) inhibitors
Discover more medicines within L01EE03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 11948W, 11961M
Country: EE	Ravimiamet	Identifier(s): 1780286, 1804407, 1872019
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 1181315001
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 175004
Country: FR	Base de données publique des médicaments	Identifier(s): 67712453
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 362853, 392452
Country: IE	Health Products Regulatory Authority	Identifier(s): 88989
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 8865
Country: IT	Agenzia del Farmaco	Identifier(s): 047197013, 047197025
Country: JP	医薬品医療機器総合機構	Identifier(s): 4291058F1024
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1086239, 1087044
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 167223
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100411243
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W68714001
Country: US	FDA, National Drug Code	Identifier(s): 70255-010