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Binimetinib

Brand names: MEKTOVI

Description

Binimetinib is an ATP-uncompetitive, reversible inhibitor of the kinase activity of mitogen-activated extracellular signal regulated kinase 1 (MEK1) and MEK2. Binimetinib inhibits activation of MEK by BRAF and inhibits MEK kinase activity. Binimetinib inhibits growth of BRAF V600 mutant melanoma cell lines.

ATC Classification

Code
Title
Category
L01EE03
Binimetinib
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EE Mitogen-activated protein kinase (MEK) inhibitors

Related medicines

MPI, EU: SmPC 2019: MEKTOVI Film-coated tablet

2D Molecule Structure

Unique Ingredient Identifier (UNII)

181R97MR71 - BINIMETINIB

 
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