SAMAZOLE

This brand name is authorized in Hong Kong

Active ingredients

The drug SAMAZOLE contains a combination of these active pharmaceutical ingredients (APIs):

1 Clotrimazole
UNII G07GZ97H65 - CLOTRIMAZOLE

Clotrimazole acts against fungi by inhibiting ergosterol synthesis. Inhibition of ergosterol synthesis leads to structural and functional impairment of the fungal cytoplasmic membrane. Clotrimazole has a broad antimycotic spectrum of action in vitro and in vivo, which includes dermatophytes, yeasts, moulds, etc.

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2 Gentamicin
UNII 8X7386QRLV - GENTAMICIN SULFATE

Gentamicin is usually bactericidal in action. Although the exact mechanism of action has not been fully elucidated, the drug appears to inhibit protein synthesis in susceptible bacteria by irreversibly binding to 30S ribosomal subunits.

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3 Triamcinolone
UNII F446C597KA - TRIAMCINOLONE ACETONIDE

Triamcinolone acetonide is a more potent derivative of triamcinolone and is approximately 8 times more potent than prednisone. Although the precise mechanism of corticosteroid anti-allergic action is unknown, corticosteroids are very effective in the treatment of allergic diseases in man. Also, local injections are thought to have an anti-inflammatory effect.

Read about Triamcinolone

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: HK Department of Health Drug Office Identifier(s): 41940

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