TEPMETKO

This brand name is authorized in Brazil, Estonia, Finland, Israel, Japan, Poland, United States

Active ingredients

The drug TEPMETKO contains one active pharmaceutical ingredient (API):

1 Tepotinib
UNII VY5YX2TQ1F - TEPOTINIB HYDROCHLORIDE

Tepotinib is a reversible Type I adenosine triphosphate (ATP)-competitive small molecule inhibitor of MET. Tepotinib blocked MET phosphorylation and MET-dependent downstream signalling in a dose-dependent manner. Tepotinib demonstrated pronounced anti-tumour activity in tumours with oncogenic activation of MET, such as METex14 skipping alterations.

Read about Tepotinib

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
TEPMETKO Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC
TEPMETKO Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L01EX21 L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EX Other protein kinase inhibitors
Discover more medicines within L01EX21

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: BR Câmara de Regulação do Mercado de Medicamentos Identifier(s): 525421090053002
Country: EE Ravimiamet Identifier(s): 1876293
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 176387
Country: IL מִשְׂרַד הַבְּרִיאוּת Identifier(s): 9037
Country: JP 医薬品医療機器総合機構 Identifier(s): 4291065F1024
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100466998
Country: US FDA, National Drug Code Identifier(s): 44087-5000

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