TONOVITAN

This brand name is authorized in Ecuador

Active ingredients

The drug TONOVITAN contains a combination of these active pharmaceutical ingredients (APIs):

1 Ferrous sulfate
UNII 39R4TAN1VT - FERROUS SULFATE

Iron sulphate is a co-factor of various enzymes necessary for the transfer of energy (eg. cytochrome oxidase, xanthine oxidase). Iron is also present in hemoglobin and myoglobin, which are essential for the transport and use of oxygen.

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2 Vitamin C
UNII PQ6CK8PD0R - ASCORBIC ACID

Ascorbic acid, coupled with dehydroascorbic acid to which it is reversibly oxidised, has a variety of functions in cellular oxidation processes. Ascorbic acid is required in several important hydroxylations, including the conversion of proline to hydroxyproline and appears to have an important role in metal ion metabolism, including the gastrointestinal absorption of iron and its transport between plasma and storage organs.

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3 Vitamin B1
UNII M572600E5P - THIAMINE HYDROCHLORIDE

Thiamine pyrophosphate (TPP), the coenzymatic form of thiamine, is involved in two main types of metabolic reactions: decarboxylation of ฮฑ-ketoacids (e.g. pyruvate, ฮฑ-ketoglutarate and branched-chain keto acids) and transketolation (e.g. among hexose and pentose phosphates). Therefore, the principal physiological role of thiamine is as a coenzyme in carbohydrate metabolism, where TPP is required for several stages in the breakdown of glucose to provide energy.

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4 Riboflavin
UNII 7N464URE7E - RIBOFLAVIN 5'-PHOSPHATE

Riboflavine is phosphorylated to flavine mononucleotide and flavine adenine dinucleotide which act as co-enzymes in the respiratory chain and in oxidative phosphorylation. Riboflavine deficiency presents with ocular symptoms, as well as lesions on the lips and at angles of the mouth.

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5 Pyridoxine
UNII 68Y4CF58BV - PYRIDOXINE HYDROCHLORIDE

Pyridoxine hydrochloride is Vitamin B6. It is converted to pyridoxal phosphate which is the co-enzyme for a variety of metabolic transformations. It is essential for human nutrition.

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6 Vitamin B12
UNII P6YC3EG204 - CYANOCOBALAMIN

Hydroxocobalamin is used in the treatment and prevention of Vitamin B12 deficiency. For adults, the daily requirement of Vitamin B12 is probably about 1 to 2 micrograms and this amount is present in most normal diets. However, Vitamin B12 only occurs in animal products, not in vegetables, and therefore strict vegetarian or vegan diets that exclude dairy products may provide an inadequate amount, although a deficiency may not be apparent for many years.

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7 Niacinamide
UNII 25X51I8RD4 - NIACINAMIDE
Read about Niacinamide
8 Folic acid
UNII 935E97BOY8 - FOLIC ACID

Folic acid is a member of the vitamin B group which is reduced in the body to tetrahydrofolate, a co-enzyme active in several metabolic processes and produces a haemopoietic response in nutritional megaloblastic anaemias. Folic acid is rapidly absorbed and widely distributed in body tissues.

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Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
B03AE03 Iron and multivitamins B Blood and blood forming organs → B03 Antianemic preparations → B03A Iron preparations → B03AE Iron in other combinations
Discover more medicines within B03AE03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: EC Agencia Nacional de Regulaciรณn, Control y Vigilancia Sanitaria Identifier(s): 02636-MAC-05-03

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