TREXATE

This brand name is authorized in New Zealand

Active ingredients

The drug TREXATE contains one active pharmaceutical ingredient (API):

1 Methotrexate
UNII YL5FZ2Y5U1 - METHOTREXATE

Methotrexate (4-amino-10-methylfolic acid) is a folic acid antagonist which inhibits the reduction of folic acid and increase of tissue cells. Methotrexate enters the cell through an active transport mechanism of reduced folates. As a result of polyglutamation of methotrexate caused by the folylpolyglutamylate enzyme, the duration of the cytotoxic effect of the drug substance in the cell increases.

Read about Methotrexate

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: NZ Medicines and Medical Devices Safety Authority Identifier(s): 15450, 15451

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