TROPINAL

This brand name is authorized in Brazil

Active ingredients

The drug TROPINAL contains a combination of these active pharmaceutical ingredients (APIs):

1 Dipyrone monohydrate
UNII 6429L0L52Y - DIPYRONE

Metamizole sodium is a pyrazolone derivative with analgesic, antipyretic and slight antiinflammatory and spasmolytic properties. It has the most potent analgesic effect of all the pyrazolone derivatives. As with other analgesics, its mechanism of action has not been elucidated in detail. It includes inhibition of prostaglandin synthesis (PGE1 and PGE2) and reversible inhibition of platelet aggregation. It inhibits cyclo-oxygenase and influences the effect of arachidonic acid.

Read about Metamizole sodium
2 Scopolamine
UNII 0GH9JX37C8 - BUTYLSCOPOLAMINE BROMIDE

Scopolamine is a naturally occurring belladonna alkaloid and has anticholinergic properties. It acts as a competitive antagonist to acetylchloline and other parasympathomimetic agents. Its mechanism of action in the central nervous system in preventing motion sickness has yet to be elucidated. Scopolamine produces classical symptoms of parasympathetic blockade.

Read about Scopolamine
3 Hyoscyamine
UNII IWT50P9S79 - HYOSCYAMINE HYDROBROMIDE

Hyoscyamine inhibits specifically the actions of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. Hyoscyamine inhibits gastrointestinal propulsive motility and decreases gastric acid secretion. It also controls excessive pharyngeal, tracheal and bronchial secretions.

Read about Hyoscyamine
4 Homatropine
UNII 68JRS2HC1C - HOMATROPINE METHYLBROMIDE
Read about Homatropine

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: BR Cรขmara de Regulaรงรฃo do Mercado de Medicamentos Identifier(s): 531625801131414, 531625802111417

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