Scopolamine Other names: Hyoscine

Chemical formula: C₁₇H₂₁NO₄  Molecular mass: 303.353 g/mol  PubChem compound: 3000322

Active ingredient description

Scopolamine is a naturally occurring belladonna alkaloid and has anticholinergic properties. It acts as a competitive antagonist to acetylchloline and other parasympathomimetic agents. Its mechanism of action in the central nervous system in preventing motion sickness has yet to be elucidated. Scopolamine produces classical symptoms of parasympathetic blockade.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A04AD01 Scopolamine A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AD Other antiemetics
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N05CM05 Scopolamine N Nervous system → N05 Psycholeptics → N05C Hypnotics and sedatives → N05CM Other hypnotics and sedatives
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S01FA02 Scopolamine S Sensory organs → S01 Ophthalmologicals → S01F Mydriatics and cycloplegics → S01FA Anticholinergics
Discover more medicines within S01FA02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
SCOPODERM Transdermal patch Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 51-34-3
DrugBank Drug: DB00747
KEGG Drug: D00138
PubChem Compound: 3000322
RxNorm Ingredient: 9601
SNOMED-CT Concept: 387409009
Scopolamine (substance)
UNII Identifier: DL48G20X8X
SCOPOLAMINE

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