TUSSOLVINA FORTE

This brand name is authorized in Ecuador

Active ingredients

The drug TUSSOLVINA FORTE contains a combination of these active pharmaceutical ingredients (APIs):

1 Chlorphenamine
UNII V1Q0O9OJ9Z - CHLORPHENIRAMINE MALEATE

Chlorphenamine is a potent antihistamine (H1-antagonist). Antihistamines diminish or abolish the actions of histamine in the body by competitive reversible blockade of histamine H1-receptor sites on tissues. Chlorphenamine also has anticholinergic activity.

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2 Guaifenesin
UNII 495W7451VQ - GUAIFENESIN

Guaifenesin is an expectorant the action of which promotes or facilitates the removal of secretions from the respiratory tract. The precise mechanism of action of guaifenesin is not known; however, it is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. In turn, this may increase the efficiency of the cough reflex and facilitate removal of the secretions. Guaifenesin is over-the-counter drug for the treatment of cough and common cold.

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3 Demorphan
UNII 9D2RTI9KYH - DEXTROMETHORPHAN HYDROBROMIDE

Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors.

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Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
R05FA02 Opium derivatives and expectorants R Respiratory system → R05 Cough and cold preparations → R05F Cough suppressants and expectorants, combinations → R05FA Opium derivatives and expectorants
Discover more medicines within R05FA02
R05FB02 Cough suppressants and expectorants R Respiratory system → R05 Cough and cold preparations → R05F Cough suppressants and expectorants, combinations → R05FB Other cough suppressants and expectorants
Discover more medicines within R05FB02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: EC Agencia Nacional de Regulación, Control y Vigilancia Sanitaria Identifier(s): 2665-MEN-0520, 6166-MAN-07-11, 650-MEN-0216

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