XALUPRINE

This brand name is authorized in Austria, Estonia, Finland, France, Ireland, Lithuania, Netherlands, Poland, United Kingdom

Active ingredients

The drug XALUPRINE contains one active pharmaceutical ingredient (API):

1 Mercaptopurine monohydrate UNII E7WED276I5 - MERCAPTOPURINE

Mercaptopurine is an inactive pro-drug which acts as a purine antagonist but requires cellular uptake and intracellular anabolism to thioguanine nucleotides for cytotoxicity. The mercaptopurine metabolites inhibit de novo purine synthesis and purine nucleotide interconversions. The thioguanine nucleotides are also incorporated into nucleic acids and this contributes to the cytotoxic effects of the active substance. Read about Mercaptopurine

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
XALUPRINE Oral suspension	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01BB02	Mercaptopurine	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BB Purine analogues
Discover more medicines within L01BB02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: EE	Ravimiamet	Identifier(s): 1558920
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 164324
Country: FR	Base de données publique des médicaments	Identifier(s): 63798857
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 219703
Country: IE	Health Products Regulatory Authority	Identifier(s): 43350
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1065399
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 103748
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100313569