ICD-10 Specific code C45.2: Mesothelioma of pericardium

Specific codes in ICD-10 are unique alphanumeric designations used to identify and categorize diseases, disorders, and conditions. They consist of 3-5 characters, including both letters and numbers, that provide a high level of detail and specificity.

Translations

Language Translation
Flag for English language  English Mesothelioma of pericardium
Flag for French language  French Mรฉsothรฉliome du pรฉricarde

Hierarchical position

Level Code Title
1 II Neoplasms
2 C00-C97 Malignant neoplasms
3 C45-C49 Malignant neoplasms of mesothelial and soft tissue
4 C45 Mesothelioma
5 C45.2 Mesothelioma of pericardium

Indicated medicines

Active Ingredient Description
Ifosfamide

Ifosfamide is an antineoplastic, a cytotoxic alkylating agent. It is a prodrug and shows no in vitro cytotoxic activity until activated by microsomal enzymes. The cytotoxic activity of ifosfamide (alkylation of the nucleophilic centres in the cells) is associated with the activated oxazaphosphorine ring hydroxylated at the C4 atom which interacts with DNA-DNA cross linking. This activity manifests itself by blocking the late S and early G2 phases of the cell cycle.