Specific codes in ICD-10 are unique alphanumeric designations used to identify and categorize diseases, disorders, and conditions. They consist of 3-5 characters, including both letters and numbers, that provide a high level of detail and specificity.
Language | Translation |
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Grand mal seizures, unspecified (with or without petit mal) |
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Crise de grand mal, sans précision (avec ou sans petit mal) |
Level | Code | Title | |
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1 | VI | Diseases of the nervous system | |
2 | G40-G47 | Episodic and paroxysmal disorders | |
3 | G40 | Epilepsy | |
4 | G40.6 | Grand mal seizures, unspecified (with or without petit mal) |
Active Ingredient |
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Perampanel is a first-in-class selective, non-competitive antagonist of the ionotropic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor on post-synaptic neurons. Glutamate is the primary excitatory neurotransmitter in the central nervous system and is implicated in a number of neurological disorders caused by neuronal overexcitation. The precise mechanism by which perampanel exerts its antiepileptic effects in humans remains to be fully elucidated. |
Topiramate is classified as a sulfamate-substituted monosaccharide. The precise mechanism by which topiramate exerts its antiseizure and migraine prophylaxis effects are unknown. |