Cimetidine is recommended before general anaesthesia in patients thought to be at risk of acid aspiration (Mendelson’s Syndrome), particularly obstetric patients during labour.
For this indication, competent medicine agencies globally authorize below treatments:
400 - 2,400 mg
From 66.667 To 400 mg 6 time(s) per day every day
In patients thought to be at risk of acid aspiration syndrome, an oral dose of 400mg can be given 90-120 minutes before induction of general anaesthesia or, in obstetric practice, at the start of labour. While such a risk persists, a dose of up to 400mg may be repeated (parenterally if appropriate) at four hourly intervals as required up to the usual daily maximum of 2.4g.