Cimetidine

Active ingredient description

Cimetidine is a histamine H2-receptor antagonist which rapidly inhibits both basal and stimulated gastric secretion of acid and reduces pepsin output. It is a reversible, competitive antagonist, and is used as an anti-ulcer drug.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Cimetidine
A Alimentary tract and metabolism → A02 Drugs for acid related disorders → A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) → A02BA H2-receptor antagonists
Discover more medicines within A02BA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK

Medicines

Cimetidine is the active ingredient of these drugs:

Drug
Countries

South Africa

South Africa

Hong Kong

Hong Kong

Hong Kong

Hong Kong

Hong Kong

Ireland

Hong Kong

Hong Kong

Hong Kong

Ecuador

South Africa

Hong Kong

Hong Kong

Hong Kong

Hong Kong

Japan

South Africa

Hong Kong

South Africa

South Africa

Hong Kong

Singapore

Hong Kong

Brazil

South Africa

South Africa

Hong Kong

Hong Kong

Tunisia

Turkey

South Africa

Hong Kong Singapore

Hong Kong

Hong Kong

Hong Kong

Hong Kong

Brazil Japan Mexico South Africa United Kingdom

Hong Kong

Cyprus

Hong Kong

Hong Kong

Hong Kong

Hong Kong

South Africa

South Africa

Hong Kong

Hong Kong

Brazil

Cyprus Hong Kong

Austria

South Africa

Hong Kong

Hong Kong

Tunisia

Hong Kong Singapore

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₀H₁₆N₆S
Molecular mass: 252.339 g/mol

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 51481-61-9
DrugBank Drug: DB00501
KEGG Drug: D00295
PubChem Compound: 2756
RxNorm Ingredient: 2541
SNOMED-CT Concept: 373541007
Cimetidine (substance)
UNII Identifier: 80061L1WGD
CIMETIDINE