Erectile dysfunction

Active Ingredient: Avanafil

Indication for Avanafil

Population group: men, only adults (18 years old or older)

Treatment of erectile dysfunction in adult men.

In order for avanafil to be effective, sexual stimulation is required.

For this indication, competent medicine agencies globally authorize below treatments:

50-200 mg once


Dosage regimens

Oral, between 50 milligrams avanafil and 200 milligrams avanafil, one dose.

Detailed description

The recommended dose is 100 mg taken as needed approximately 15 to 30 minutes before sexual activity. Based on individual efficacy and tolerability, the dose may be increased to a maximum dose of 200 mg or decreased to 50 mg. The maximum recommended dosing frequency is once per day. Sexual stimulation is required for a response to treatment.

Dosage considerations

It should be taken 15 to 30 minutes before sexual activity.

If avanafil is taken with food, the onset of activity may be delayed compared to the fasted state.

Active ingredient


Avanafil is a highly selective and potent, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5. When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by avanafil produces increased levels of cGMP in the corpus cavernosum of the penis. This results in smooth muscle relaxation and inflow of blood into the penile tissues, thereby producing an erection.

Read more about Avanafil

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