Primary hypercholesterolaemia, mixed dyslipidaemia

Active Ingredient: Rosuvastatin

Indication for Rosuvastatin

Population group: only elderly (65 years old or older)

Adults, adolescents and children aged 6 years or older with primary hypercholesterolaemia (type IIa including heterozygous familial hypercholesterolaemia) or mixed dyslipidaemia (type IIb) as an adjunct to diet when response to diet and other non-pharmacological treatments (e.g. exercise, weight reduction) is inadequate.

For this indication, competent medicine agencies globally authorize below treatments:

5-40 mg once daily

Route of admnistration

Oral

Defined daily dose

5 - 40 mg

Dosage regimen

From 5 To 40 mg once every day

Loading dose

5 mg

Detailed description

A start dose of 5 mg is recommended in patients >70 years. No other dose adjustment is necessary in relation to age.

Dosage considerations

It may be given at any time of day, with or without food.

Active ingredient

Rosuvastatin

Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase. Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.

Read more about Rosuvastatin

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