Active Ingredient: Clonidine
Clonidine is indicated for the treatment of all grades of essential and secondary hypertension.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
150 - 600 ug
From 50 To 200 ug 3 time(s) per day every day
150 ug
Oral treatment should commence with 50-100 micrograms three times daily. This dose should be increased gradually every second or third day until control is achieved. Most patients will be controlled on divided daily doses of 300-1200 micrograms. However, some patients may require higher doses, e.g. 1800 micrograms or more.
Clonidine may be added to an existing antihypertensive regimen where blood pressure control has not been satisfactorily achieved. If side-effects with existing therapy are troublesome the concomitant use of clonidine may allow a lower dose of the established regimen to be employed. Patients changing treatment should have their existing therapy reduced gradually whilst clonidine is added to their regimen.
Patients undergoing anaesthesia should continue their clonidine treatment before, during and after anaesthesia using oral or i.v. administration according to individual circumstances.
No specific information on the use of this product in the elderly is available. Clinical trials have included patients over 65 years and no adverse reactions specific to this age group have been reported.
Intravenous
150 - 750 ug
From 50 To 250 ug 3 time(s) per day every day
150 ug
In hypertensive crises 150 to 300 micrograms should be given by slow intravenous injection. This dose may be repeated up to a maximum of 750 micrograms in a 24 hour period.
Patients undergoing anaesthesia should continue their clonidine treatment before, during and after anaesthesia using oral or intravenous administration according to individual circumstances.
Intravenous injection of clonidine should be given slowly over 10-15 minutes to avoid a possible transient pressor effect.
Clonidine injection solution is compatible with 0.9% sodium chloride solution and with 5% Dextrose solution.
Intravenous injection of clonidine should be given slowly over 10-15 minutes to avoid a possible transient pressor effect.
Clonidine injection solution is compatible with 0.9% sodium chloride solution and with 5% Dextrose solution.
Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.
