Chemical formula: C₉H₉Cl₂N₃ Molecular mass: 230.094 g/mol PubChem compound: 2803
Clonidine has been shown to have both central and peripheral sites of action. With long-term treatment clonidine reduces the responsiveness of peripheral vessels to vasoconstrictor and vasodilator substances and to sympathetic nerve stimulation. Early in treatment, however, blood pressure reduction is associated with a central reduction of sympathetic outflow and increased vagal tone.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C02AC01 | Clonidine | C Cardiovascular system → C02 Antihypertensives → C02A Antiadrenergic agents, centrally acting → C02AC Imidazoline receptor agonists |
| N02CX02 | Clonidine | N Nervous system → N02 Analgesics → N02C Antimigraine preparations → N02CX Other antimigraine preparations |
| S01EA04 | Clonidine | S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EA Sympathomimetics in glaucoma therapy |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CATAPRES Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| CATAPRES Ampoules | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Clonidine is an active ingredient of these brands:
United States (US)Australia (AU)
Austria (AT)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Ireland (IE)
Israel (IL)
Japan (JP)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)
South Africa (ZA)
Spain (ES)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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