For this indication, competent medicine agencies globally authorize below treatments:
Intravenous
6 - 6 g
From 2 To 2 g 3 time(s) per day every day for 14 day(s)
A daily dose of 6 g cefotaxime (14 to 21 days duration). The daily dose was generally administered divided into 3 parts (2 g cefotaxime 3 times daily).
For IV, cefotaxime for injection 500mg is dissolved in at least 2 ml water for injections, Cefotaxime for injection 1 g in at least 4 ml and subsequently injected directly into the vein over 3 to 5 minutes or after clamping of the infusion tube into the distal end of the tube. During post-marketing surveillance, potentially life-threatening arrhythmia has been reported in a very few patients who received rapid intravenous administration of cefotaxime through a central venous catheter.
For brief infusion 2g of cefotaxime for injection is dissolved in 100 ml of isotonic sodium chloride or glucose solution and subsequently IV infused over 50 to 60 minutes. Another compatible infusion solution can also be used for the solution.