Active ingredients: Cefotaxime
Cefotaxime Sodium for Injection.
Powder for solution for injection or infusion.
Vials containing a white to slightly yellow powder, which when dissolved in Water for Injections forms a straw coloured solution. The intensity of the colour of the solution may vary but this does not indicate differences in potency or safety.
|Cefotaxime (as cefotaxime sodium) per vial||Diluent to be added||Final concentration of solution|
|500 mg||2 ml||500 mg/2.2 ml|
|1 g||4 ml||1 g/4.4 ml|
A quantity of cefotaxime sodium equivalent to 1 g cefotaxime contains approximately 50 mg (2.2 mmol) of sodium.
For excipients see 6.1.
Cefotaxime exerts its action by binding to one or more of the penicillin-binding proteins (PBPs) which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thereby inhibiting cell wall synthesis.
500 mg and 1 g presentations in 10 ml glass vials closed with rubber stoppers and sealed with aluminium caps.
Packaged singly or in cartons of 10, 25 or 50.
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