Schizophrenia

Active Ingredient: Aripiprazole

Indication for Aripiprazole

Population group: only adolescents (12 years - 18 years old)

Aripiprazole is indicated for the treatment of schizophrenia in adults.

For this indication, competent medicine agencies globally authorize below treatments:

2-30 mg once a day

Route of admnistration

Oral

Defined daily dose

2 - 30 mg

Dosage regimen

From 2 To 30 mg once every day

Detailed description

Schizophrenia in adolescents aged 15 years and older

The recommended dose for aripiprazole is 10 mg/day administered on a once-a-day schedule without regard to meals. Treatment should be initiated at 2 mg (using aripiprazole oral solution 1 mg/ml) for 2 days, titrated to 5 mg for 2 additional days to reach the recommended daily dose of 10 mg. When appropriate, subsequent dose increases should be administered in 5 mg increments without exceeding the maximum daily dose of 30 mg. Aripiprazole is effective in a dose range of 10 to 30 mg/day. Enhanced efficacy at doses higher than a daily dose of 10 mg has not been demonstrated although individual patients may benefit from a higher dose. Aripiprazole is not recommended for use in patients with schizophrenia below 15 years of age due to insufficient data on safety and efficacy.

Active ingredient

Aripiprazole

It has been proposed that aripiprazole’s efficacy in schizophrenia and Bipolar I Disorder is mediated through a combination of partial agonism at dopamine D2 and serotonin 5-HT1A receptors and antagonism of serotonin 5-HT2A receptors.

Read more about Aripiprazole

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