Aripiprazole

Chemical formula: C₂₃H₂₇Cl₂N₃O₂  Molecular mass: 448.385 g/mol  PubChem compound: 60795

Active ingredient description

It has been proposed that aripiprazole’s efficacy in schizophrenia and Bipolar I Disorder is mediated through a combination of partial agonism at dopamine D2 and serotonin 5-HT1A receptors and antagonism of serotonin 5-HT2A receptors.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N05AX12 Aripiprazole N Nervous system → N05 Psycholeptics → N05A Antipsychotics → N05AX Other antipsychotics
Discover more medicines within N05AX12

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ABILIFY Tablet European Medicines Agency (EU) MPI, EU: SmPC
ABILIFY Solution for injection European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 129722-12-9
DrugBank Drug: DB01238
KEGG Drug: D01164
PubChem Compound: 60795
RxNorm Ingredient: 89013
SNOMED-CT Concept: 406784005
Aripiprazole (substance)
UNII Identifier: 82VFR53I78
ARIPIPRAZOLE

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