Cardiac arrest

Indication for Epinephrine

Population group: Suitable for both men and women, only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

For this indication, competent medicine agencies globally authorize below treatments:

10 micrograms/kg repeated every 3-5 minutes until return of spontaneous circulation

Route of admnistration

Intravenous

Defined daily dose

10 - 10 ug per kg of body weight

Dosage regimen

From 10 To 10 ug per kg of body weight once every day

Detailed description

0.1 ml/kg of 1:10,000 solution (10 micrograms/kg) to a maximum single dose of 10 ml of 1:10,000 solution (1 mg), repeated every 3-5 minutes until return of spontaneous circulation.

100 micrograms/kg repeated every 3-5 minutes until return of spontaneous circulation

Route of admnistration

Endotracheal

Defined daily dose

100 - 100 ug per kg of body weight

Dosage regimen

From 100 To 100 ug per kg of body weight once every day

Detailed description

Endotracheal use (any body weight) should only be considered as a last resort if no other route of administration is accessible, at a dose of 1 ml/kg of 1:10,000 solution (100 micrograms/kg) to a maximum of single dose of 25 ml of 1:10,000 solution (2.5 mg).

Active ingredient

Epinephrine is a direct acting sympathomimetic agent, which exerts effects on both α and β adrenoceptors. It has more pronounced effects on β than on α adrenoceptors, although α effects prevail at high doses. The effects of adrenaline include increased rate and force of cardiac contraction, cutaneous vasoconstriction and broncho-dilatation.

Read more about Epinephrine

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