Epinephrine Other names: Adrenaline

Chemical formula: C₉H₁₃NO₃  Molecular mass: 183.204 g/mol  PubChem compound: 5816

Active ingredient description

Epinephrine is a direct acting sympathomimetic agent, which exerts effects on both α and β adrenoceptors. It has more pronounced effects on β than on α adrenoceptors, although α effects prevail at high doses. The effects of adrenaline include increased rate and force of cardiac contraction, cutaneous vasoconstriction and broncho-dilatation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A01AD01 Epinephrine A Alimentary tract and metabolism → A01 Stomatological preparations → A01A Stomatological preparations → A01AD Other agents for local oral treatment
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B02BC09 Epinephrine B Blood and blood forming organs → B02 Antihemorrhagics → B02B Vitamin K and other hemostatics → B02BC Local hemostatics
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C01CA24 Epinephrine C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CA Adrenergic and dopaminergic agents
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R01AA14 Epinephrine R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AA Sympathomimetics, plain
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R03AA01 Epinephrine R Respiratory system → R03 Drugs for obstructive airway diseases → R03A Adrenergics, inhalants → R03AA Alpha- and beta-adrenoreceptor agonists
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S01EA01 Epinephrine S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EA Sympathomimetics in glaucoma therapy
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Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ADRENALINE AGUETTANT Solution for injection in pre-filled syringe Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 51-42-3
CAS Substance: 51-43-4
CAS Substance: 55-31-2
DrugBank Drug: DB00668
KEGG Drug: D00095
PubChem Compound: 5816
RxNorm Ingredient: 3992
SNOMED-CT Concept: 372575003
Epinephrine (substance)
SNOMED-CT Concept: 387362001
Epinephrine (substance)
SNOMED-CT Concept: 78890004
Epinephrine (substance)
UNII Identifier: YKH834O4BH


Epinephrine is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

  • EPIPEN as Adrenaline
  • JEXT as Adrenaline


Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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