Cilazapril is indicated for the treatment of chronic heart failure.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
0.5 - 5 mg
From 0.5 To 5 mg once every day
0.5 mg
Therapy with cilazapril should be initiated at a recommended starting dose of 0.5 mg once daily under close medical supervision. This dose should be maintained for about 1 week. If this dose has been well tolerated it may be increased in weekly intervals and according to the clinical status of the patient to 1.0 mg or 2.5 mg. The maximum daily dose for these patients is 5.0 mg. The posology recommendation for cilazapril in chronic heart failure is based on effects on symptomatic improvement, rather than on data showing that cilazapril reduces morbidity and mortality in this patient group.
As food intake has no clinically significant influence on absorption, cilazapril can be administered before or after a meal. The dose should always be taken at about the same time of day.