Active Ingredient: Misoprostol
Medical termination of developing intra-uterine pregnancy, in sequential use with mifepristone, up to 49 days of amenorrhea.
For this indication, competent medicine agencies globally authorize below treatments:
Oral
400 - 400 ug
From 400 To 400 ug once every day
Misoprostol is taken as a single 400 microgram oral dose 36 to 48 hours after taking a single 600 mg oral dose of mifepristone. Information on the posology of mifepristone can be found in the product information of mifepristone.
Vomiting within 30 minutes after the intake could lead to a decrease in misoprostol efficacy: oral intake of a new misoprostol 400 microgram tablet is recommended in this case.
Vaginal
200 - 200 ug
From 200 To 200 ug once every day
The maximum recommended dose is misoprostol 200 micrograms by a vaginal delivery system, at a rate of approximately 7 micrograms/hour over a period of 24 hours.
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