Chemical formula: C₂₂H₃₈O₅  Molecular mass: 382.534 g/mol  PubChem compound: 5282381

Active ingredient description

Misoprostol is an analogue of naturally occurring prostaglandin E1 which promotes peptic ulcer healing and symptomatic relief. Misoprostol protects the gastroduodenal mucosa by inhibiting basal, stimulated and nocturnal acid secretion and by reducing the volume of gastric secretions, the proteolytic activity of the gastric fluid, and increasing bicarbonate and mucus secretion.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A02BB01 Misoprostol A Alimentary tract and metabolism → A02 Drugs for acid related disorders → A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) → A02BB Prostaglandins
Discover more medicines within A02BB01
G02AD06 Misoprostol G Genito urinary system and sex hormones → G02 Other gynecologicals → G02A Oxytocics → G02AD Prostaglandins
Discover more medicines within G02AD06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
TOPOGYNE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CYTOTEC Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MYSODELLE Vaginal delivery system Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 59122-46-2
DrugBank Drug: DB00929
KEGG Drug: D00419
PubChem Compound: 5282381
RxNorm Ingredient: 42331
SNOMED-CT Concept: 387242007
Misoprostol (substance)
UNII Identifier: 0E43V0BB57


Misoprostol is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.