ARTHROTEC

This brand name is authorized in Austria, Canada, Estonia, Finland, Ireland, Nigeria, Netherlands, Poland, Romania, United Kingdom, United States, South Africa

Active ingredients

The drug ARTHROTEC contains a combination of these active pharmaceutical ingredients (APIs):

1 Diclofenac
UNII QTG126297Q - DICLOFENAC SODIUM

Diclofenac is a non-steroidal anti-inflammatory drug. The mechanism of action of diclofenac in AK may be related to the inhibition of the cycloxygenase pathway leading to reduced prostaglandin E2 (PGE2) synthesis. In addition, immunohistochemistry (IHC) from skin biopsies ac revealed that the clinical effects of diclofenac in AK are primarily due to anti-inflammatory, anti-angiogenic and possibly anti-proliferative effects and apoptosis-inducing mechanisms.

Read about Diclofenac
2 Misoprostol
UNII 0E43V0BB57 - MISOPROSTOL

Misoprostol is an analogue of naturally occurring prostaglandin E1 which promotes peptic ulcer healing and symptomatic relief. Misoprostol protects the gastroduodenal mucosa by inhibiting basal, stimulated and nocturnal acid secretion and by reducing the volume of gastric secretions, the proteolytic activity of the gastric fluid, and increasing bicarbonate and mucus secretion.

Read about Misoprostol

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
M01AB55 Diclofenac, combinations M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AB Acetic acid derivatives and related substances
Discover more medicines within M01AB55

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: CA Health Products and Food Branch Identifier(s): 01917056, 02229837
Country: EE Ravimiamet Identifier(s): 1088399
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 154591, 154708, 431759, 431783
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 299783, 299785, 31603, 31617, 376209, 377155
Country: IE Health Products Regulatory Authority Identifier(s): 13102, 14426, 14604, 14661
Country: NG Registered Drug Product Database Identifier(s): A4-3491
Country: NL Z-Index G-Standaard, PRK Identifier(s): 84514, 84522
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100001491, 100087216, 100348763
Country: RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale Identifier(s): W65281001, W65281002
Country: US FDA, National Drug Code Identifier(s): 0025-1411, 0025-1421
Country: ZA Health Products Regulatory Authority Identifier(s): 28/3.1/0440, 32/3.1/0353

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