Diclofenac
Also known as: Diclofenac sodium
Active ingredient description
Diclofenac is a non-steroidal anti-inflammatory drug. The mechanism of action of diclofenac in AK may be related to the inhibition of the cycloxygenase pathway leading to reduced prostaglandin E2 (PGE2) synthesis. In addition, immunohistochemistry (IHC) from skin biopsies ac revealed that the clinical effects of diclofenac in AK are primarily due to anti-inflammatory, anti-angiogenic and possibly anti-proliferative effects and apoptosis-inducing mechanisms.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Medicines
Diclofenac is the active ingredient of these drugs:
Ecuador
Ecuador
Ecuador
Hong Kong
Poland
Poland United Kingdom
Cyprus Estonia Hong Kong Singapore
Hong Kong Singapore
South Africa
France
Hong Kong
Cyprus
Hong Kong
Hong Kong
Germany
Brazil Ecuador
South Africa
Brazil
Brazil
Ecuador
Brazil
Brazil
Canada United States
Hong Kong
South Africa
South Africa
Brazil Cyprus Ecuador Estonia Hong Kong
Brazil
Brazil
Hong Kong Singapore
Hong Kong Singapore
Hong Kong
Australia
Lithuania
Italy
Austria
Austria Italy
Hong Kong
Ecuador
Brazil
Spain
Brazil Cyprus Estonia Germany Ireland
Austria
Poland
New Zealand
Ecuador
South Africa
South Africa
United Kingdom
Austria
Finland Netherlands Poland Spain Tunisia
Brazil
Austria
Austria
Estonia Lithuania Poland
Ecuador
Hong Kong
Ecuador
Spain
Poland
Brazil Italy
Brazil
Poland
South Africa
Estonia Lithuania United Kingdom
Hong Kong
Hong Kong Poland Singapore
Hong Kong Tunisia
New Zealand South Africa
South Africa
Spain
Germany
Poland United Kingdom
Estonia Lithuania
Finland
Ecuador
Tunisia
Hong Kong
Ecuador
Hong Kong Singapore
Lithuania
Poland
Hong Kong
Italy Poland
Hong Kong
Austria
Poland
Poland
Germany
Ecuador Germany
Germany
Poland
Hong Kong
Ecuador
Hong Kong
Estonia Finland Lithuania Poland
Poland
Hong Kong South Africa Tunisia
Hong Kong
Hong Kong Singapore
Cyprus Ireland
Hong Kong
South Africa
Hong Kong
Hong Kong
Hong Kong
Ecuador
Hong Kong
Spain
Hong Kong
Hong Kong
Mexico
South Africa
Ecuador South Africa
Ecuador
Ecuador
Brazil
Ecuador
Spain
Spain
Ecuador
Ecuador
Spain
Austria
Singapore
Brazil
South Africa
Ecuador
United Kingdom
Germany
United Kingdom
France
Hong Kong
Hong Kong
Brazil
Estonia Poland
Estonia
Lithuania
Australia Hong Kong Singapore
Hong Kong Singapore
Italy
Brazil
Brazil
Italy
South Africa
Brazil
Ecuador
Austria Cyprus France Hong Kong Ireland
Poland
Ecuador
Ecuador
Hong Kong
Brazil
Italy
Brazil
Hong Kong
South Africa
Hong Kong
Hong Kong
Hong Kong
South Africa
Brazil
Brazil
Hong Kong
Ireland Poland Tunisia
Hong Kong
South Africa
Hong Kong
Ecuador Mexico
Hong Kong
United States
Hong Kong
Hong Kong
Poland
Brazil
Tunisia
Finland United Kingdom
South Africa
Ireland
Netherlands Poland
Estonia Lithuania Poland
Hong Kong
Brazil
Singapore
Singapore
Brazil
Brazil
South Africa
Lithuania
Ecuador
Estonia Hong Kong Lithuania Poland Singapore
New Zealand
Estonia Lithuania
Hong Kong
South Africa
Austria Canada United States
South Africa
Brazil
Singapore
Ecuador
Brazil
Hong Kong
Hong Kong
Hong Kong
Hong Kong Singapore
Cyprus Hong Kong Singapore
Hong Kong
Singapore
Hong Kong
Hong Kong
Cyprus Hong Kong
Hong Kong
Hong Kong
Hong Kong
Brazil
Austria Italy Poland Spain United Kingdom
Australia Austria Finland France Ireland
Brazil
Hong Kong
Cyprus Hong Kong
Austria
Hong Kong
Hong Kong
Austria
Ecuador
Hong Kong
Singapore
Hong Kong
Lithuania
Hong Kong
Hong Kong
Hong Kong
South Africa
Poland
Hong Kong
Hong Kong
Hong Kong
Estonia Lithuania Poland
Cyprus
Hong Kong
Tunisia
Hong Kong
Austria Spain
Australia Austria Brazil Canada Cyprus
South Africa
Mexico
Germany
Germany
Lithuania Tunisia
Estonia Ireland United Kingdom
Ireland Italy New Zealand Singapore
Hong Kong
Hong Kong
Estonia
Hong Kong Singapore
Hong Kong
Hong Kong
Hong Kong
Tunisia
Tunisia
Hong Kong Lithuania
Hong Kong
Tunisia
Hong Kong
Hong Kong
United States
Hong Kong
Hong Kong Singapore
Spain
Ecuador United States
Brazil
Hong Kong
Diclofenac is also found within below combination drugs:
ADORLAN , ALGESIA , ALGINAC , ANALGAN PLUS , ARTHROCOMB , ARTHROTEC , ARTROTEC , BERALDOL , BERALMAT , BESEROL , BETASUN , CECLOVA , CLOFEN T , CODATEN , COMPFENAK , CONRELAX PLUS , CONTRACTIL PLUS , DICASEN , DICLO-B , DICLODUO COMBI , DICLOPAR DUO , DICLOPRAM , DICLORATIO , DICLOVIT , DIOMPRAZ , DIOXAFLEX DUO , DIOXAFLEX PLUS , DOLAREN , DOLKE FORTE , DOLO-NEUROBION , DOLOAPROXOL DUAL FORTE , DOLODRAN EXTRA FORTE , DOLORLESS , DOLOSTOP FORTE , DURAPAIN , EUTRADIC , FLEXALGIN , FRAGESIC , INFRALAX , LERTUS FORTE , MIOFLEX A , MISOFEN , NEODOLPASSE , NEUTALIN , NOVO KLOSIDOL , OLFEN-75 , PARALGEN DICLO , PARNAC , PRESTOFLAM LD , QUITADOL , RHEUTHROTEC , TAFIROL AC , TANDENE , TANDERALGIN , TANDRIFLAN , TANDRILAX , TAPAIN , TENDUM , TENSORELAX DICLO , TORFLAY , TORSILAX , TRADOXIL D , TRAZINAC , TRILAX , TRIMUSK , VENOZEL
Structural formula
Chemical formula: C₁₄H₁₁Cl₂NO₂
Molecular mass: 296.149 g/mol
3D molecular structure