Active ingredients: Diclofenac
Diclodent 0.74 mg/ml Mouthwash (Oromucosal Solution).
Diclofenac 0.74 mg/ml Mouthwash.
Oromucosal solution (Mouthwash).
100 ml of the solution contains:
Active substance: 0.074 %w/v Diclofenac free acid.
Excipients with known effect:
Sorbitol (E420) 50% w/v
Sodium Benzoate (E211) 1% w/v
Ponceau Red E124 0.005% w/v
For a full list of excipients, see section 6.1.
Diclofenac is a non-steroidal anti-inflammatory drug. The mechanism of action of diclofenac in AK may be related to the inhibition of the cycloxygenase pathway leading to reduced prostaglandin E2 (PGE2) synthesis. In addition, immunohistochemistry (IHC) from skin biopsies ac revealed that the clinical effects of diclofenac in AK are primarily due to anti-inflammatory, anti-angiogenic and possibly anti-proliferative effects and apoptosis-inducing mechanisms.
Sorbitol liquid non crystallising (E420)
Choline
Sodium benzoate (E211)
Disodium edetate
Acesulfame potassium (E950)
Peppermint oil
Peach flavour
Ponceau red E124
Purified water
200ml amber (type III) glass bottle with child resistance polypropylene closure.
Morningside Healthcare Ltd, 115 Narborough Road, Leicester, LE3 0PA, UK
PL 20117/0112
03/03/2016