Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2016 Publisher: Morningside Healthcare Ltd, 115 Narborough Road, Leicester, LE3 0PA, UK
Diclodent 0.74 mg/ml Mouthwash (Oromucosal Solution).
Diclofenac 0.74 mg/ml Mouthwash.
| Pharmaceutical Form |
|---|
|
Oromucosal solution (Mouthwash). |
100 ml of the solution contains:
Active substance: 0.074 %w/v Diclofenac free acid.
Excipients with known effect:
Sorbitol (E420) 50% w/v
Sodium Benzoate (E211) 1% w/v
Ponceau Red E124 0.005% w/v
For a full list of excipients, see section 6.1.
| Active Ingredient |
|---|
|
Diclofenac is a non-steroidal anti-inflammatory drug. The mechanism of action of diclofenac in AK may be related to the inhibition of the cycloxygenase pathway leading to reduced prostaglandin E2 (PGE2) synthesis. In addition, immunohistochemistry (IHC) from skin biopsies ac revealed that the clinical effects of diclofenac in AK are primarily due to anti-inflammatory, anti-angiogenic and possibly anti-proliferative effects and apoptosis-inducing mechanisms. |
| List of Excipients |
|---|
|
Sorbitol liquid non crystallising (E420) |
200ml amber (type III) glass bottle with child resistance polypropylene closure.
Morningside Healthcare Ltd, 115 Narborough Road, Leicester, LE3 0PA, UK
PL 20117/0112
03/03/2016
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