Central retinal vein occlusion with macular edema

Active Ingredient: Dexamethasone

Indication for Dexamethasone

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

700 μg once

Route of admnistration

Intravitreal

Defined daily dose

700 - 700 ug

Dosage regimen

From 700 To 700 ug once every day for 1 day(s)

Detailed description

The recommended dose is one implant of 700 μg dexamethasone to be administered intra-vitreally to the affected eye. Administration to both eyes concurrently is not recommended.

Repeat doses should be considered when a patient experiences a response to treatment followed subsequently by a loss in visual acuity and in the physician’s opinion may benefit from retreatment without being exposed to significant risk.

Patients who experience and retain improved vision should not be retreated. Patients who experience deterioration in vision, which is not slowed by dexamethasone, should not be retreated.

There is only very limited information on repeat dosing intervals less than 6 months.

For information concerning the current safety experience of repeat administrations beyond 2 implants in posterior segment non-infectious uveitis and Retinal Vein Occlusion.

Patients should be monitored following the injection to permit early treatment if an infection or increased intraocular pressure occurs.

Active ingredient

Dexamethasone

Dexamethasone is a synthetic glucocorticoid; it combines high anti-inflammatory effects with low mineralocorticoid activity. It has an approximately 7 times greater anti-inflammatory potency than prednisolone, another commonly prescribed corticosteroid. At high doses it reduces the immune response.

Read more about Dexamethasone

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