Prophylaxis of NSAID-induced ulcers

Indication for Misoprostol

Population group: Suitable for both men and women, only adults (18 years old or older)
Therapeutic intent: Preventive action

Misoprostol can be used for the prophylaxis of NSAID-induced ulcers.

For this indication, competent medicine agencies globally authorize below treatments:

400-800 μg in 2-4 divided doses daily

Route of admnistration


Defined daily dose

400 - 800 ug

Dosage regimen

From 100 To 200 ug 4 time(s) per day every day

Detailed description

200 micrograms twice daily, three times daily or four times daily. Treatment can be continued as required. Dosage should be individualised according to the clinical condition of each patient.

Dosage considerations

It should be taken with breakfast and/or each main meal and at bedtime.

Active ingredient

Misoprostol is an analogue of naturally occurring prostaglandin E1 which promotes peptic ulcer healing and symptomatic relief. Misoprostol protects the gastroduodenal mucosa by inhibiting basal, stimulated and nocturnal acid secretion and by reducing the volume of gastric secretions, the proteolytic activity of the gastric fluid, and increasing bicarbonate and mucus secretion.

Read more about Misoprostol

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