Duodenal ulcer, gastric ulcer

Indication for Misoprostol

Population group: Suitable for both men and women, only adults (18 years old or older)

Misoprostol is indicated for the healing of duodenal ulcer and gastric ulcer including those induced by nonsteroidal anti-inflammatory drugs (NSAID) in arthritic patients at risk, whilst continuing their NSAID therapy.

For this indication, competent medicine agencies globally authorize below treatments:

800 μg in 2-4 divided doses daily

Route of admnistration

Oral

Defined daily dose

800 - 800 ug

Dosage regimen

From 200 To 200 ug 4 time(s) per day every day

Detailed description

800 micrograms daily in two or four divided doses taken with breakfast and/or each main meal and at bedtime.

Treatment should be given initially for at least 4 weeks even if symptomatic relief has been achieved sooner. In most patients ulcers will be healed in 4 weeks but treatment may be continued for up to 8 weeks if required. If the ulcer relapses further treatment courses may be given.

Dosage considerations

It should be taken with breakfast and/or each main meal and at bedtime.

Active ingredient

Misoprostol is an analogue of naturally occurring prostaglandin E1 which promotes peptic ulcer healing and symptomatic relief. Misoprostol protects the gastroduodenal mucosa by inhibiting basal, stimulated and nocturnal acid secretion and by reducing the volume of gastric secretions, the proteolytic activity of the gastric fluid, and increasing bicarbonate and mucus secretion.

Read more about Misoprostol

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