Primary hyperlipidemia

Active Ingredient: Atorvastatin

Indication for Atorvastatin

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

As an adjunct to diet to reduce low-density lipoprotein cholesterol (LDL-C) in adults with primary hyperlipidemia.

For this indication, competent medicine agencies globally authorize below treatments:

10-20 mg once daily for at least 4 weeks and thereafter 10-80 mg once daily

For:

Dosage regimens

Oral, between 10 milligrams atorvastatin and 20 milligrams atorvastatin, once daily, over the duration of 4 weeks. Afterwards, oral, between 10 milligrams atorvastatin and 80 milligrams atorvastatin, once daily. The maximum allowed total dose is 80 milligrams atorvastatin daily.

Detailed description

The recommended starting dosage of atorvastatin is 10 mg to 20 mg once daily. The dosage range is 10 mg to 80 mg once daily. Patients who require reduction in LDL-C greater than 45% may be started at 40 mg once daily.

Assess LDL-C when clinically appropriate, as early as 4 weeks after initiating atorvastatin, and adjust the dosage if necessary.

Dosage considerations

Take atorvastatin orally once daily at any time of the day, with or without food.

Active ingredient

Atorvastatin

Atorvastatin is a selective, competitive inhibitor of HMG-CoA reductase. Atorvastatin lowers plasma cholesterol and lipoprotein serum concentrations by inhibiting HMG-CoA reductase and subsequently cholesterol biosynthesis in the liver and increases the number of hepatic LDL receptors on the cell surface for enhanced uptake and catabolism of LDL.

Read more about Atorvastatin

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