Atorvastatin C₃₃H₃₅FN₂O₅

Active ingredient description

Atorvastatin is a selective, competitive inhibitor of HMG-CoA reductase. Atorvastatin lowers plasma cholesterol and lipoprotein serum concentrations by inhibiting HMG-CoA reductase and subsequently cholesterol biosynthesis in the liver and increases the number of hepatic LDL receptors on the cell surface for enhanced uptake and catabolism of LDL.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Atorvastatin
C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AA HMG CoA reductase inhibitors
Discover more medicines within C10AA05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
FDA, National Drug Code (US)
Structured Product Labeling (SPL/PLR)
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₃₃H₃₅FN₂O₅
Molecular mass: 558.64 g/mol

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 134523-00-5
DrugBank Drug: DB01076
KEGG Drug: D07474
PubChem Compound: 60823
RxNorm Ingredient: 83367
SNOMED-CT Concept: 373444002
Atorvastatin (substance)
UNII Identifier: A0JWA85V8F
ATORVASTATIN

Medicines

Atorvastatin is an active ingredient of these brands:

United States (US)

  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE

Australia (AU)

Austria (AT)

Brazil (BR)

  • AT-LOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATEROMA as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORLESS as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORVASTEROL as ATORVASTATIN CALCIUM TRIHYDRATE
  • CITALOR as Atorvastatin calcium
  • CORASTORVA as Atorvastatin calcium
  • KOLEVAS as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPIGRAN as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPISTAT as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPTHAL as ATORVASTATIN CALCIUM TRIHYDRATE
  • LUMIRARTE as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVILIP as ATORVASTATIN CALCIUM TRIHYDRATE
  • VAST as ATORVASTATIN CALCIUM TRIHYDRATE

Canada (CA)

  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

  • ASTATOR
  • ATILEN
  • ATORGAMMA as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • LOPAMOL
  • SORTIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVACARD as Atorvastatin calcium
  • TULIP as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) AMALORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) AMSTADIN
  • (combination) DUPLECOR as ATORVASTATIN LYSINE
  • (combination) EUVASCOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TORZELIP as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TRIVERAM as ATORVASTATIN CALCIUM TRIHYDRATE

Finland (FI)

  • ATORBIR as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPISTAD as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • ORBEOS as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) EUVASCOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TRIVERAM as ATORVASTATIN CALCIUM TRIHYDRATE

France (FR)

  • TAHOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) LIPERCOSYL as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) LIPTRUZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) RESELIP as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TRIVERAM as ATORVASTATIN CALCIUM TRIHYDRATE

Germany (DE)

  • ATORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • SORTIS as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ATORIMIB as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) LIPTRUZET as ATORVASTATIN CALCIUM TRIHYDRATE

Hong Kong (HK)

  • ATACOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORKEY as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORLIP as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATOTY as ATORVASTATIN CALCIUM TRIHYDRATE
  • BIOTOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • CARATO as ATORVASTATIN CALCIUM TRIHYDRATE
  • CHLOVAS as ATORVASTATIN CALCIUM TRIHYDRATE
  • DIVATOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • JEMATOR as Atorvastatin calcium
  • LESSTROL as Atorvastatin calcium
  • LIPICURE as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPIDUCE as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPIGET as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPIKHAN as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPISTAD as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPIVAS as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPIWON as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPOMID as ATORVASTATIN CALCIUM TRIHYDRATE
  • ORVAKLINE as ATORVASTATIN CALCIUM TRIHYDRATE
  • SYNPITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVATEC as ATORVASTATIN CALCIUM TRIHYDRATE
  • VASPITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • XARATOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • XTOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CODUWON as Atorvastatin calcium

Ireland (IE)

  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) LIPERCOSYL as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) LIPERTANCE
  • (combination) TRINOMIA

Italy (IT)

  • ARKAS
  • ATORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • KOLESTER as ATORVASTATIN CALCIUM TRIHYDRATE
  • MELEMIB as ATORVASTATIN CALCIUM TRIHYDRATE
  • OMEGASTATIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • SOPAVI as ATORVASTATIN CALCIUM TRIHYDRATE
  • TAXAT as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVACOL as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVAST as ATORVASTATIN CALCIUM TRIHYDRATE
  • TOTALIP as ATORVASTATIN CALCIUM TRIHYDRATE
  • TOVANIRA as ATORVASTATIN CALCIUM TRIHYDRATE
  • VASTAT as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ANCILLEG as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) EZEVAST as ATORVASTATIN CALCIUM TRIHYDRATE

Japan (JP)

  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) AMALUET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE

Lithuania (LT)

  • ABARAN as ATORVASTATIN CALCIUM TRIHYDRATE
  • ASTATOR
  • ATORGAMMA as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • LOPAMOL
  • MODLIP
  • SORTIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVACARD as Atorvastatin calcium
  • TORVARIN as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ATORDAPIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) EUVASCOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) EXTROTAN as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TACERNOL as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TORZELIP as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TRIVERAM as ATORVASTATIN CALCIUM TRIHYDRATE

Malta (MT)

  • ATORAB as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE

Mexico (MX)

  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE

Netherlands (NL)

  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE

New Zealand (NZ)

Nigeria (NG)

  • ATORKEM as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATOSTOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATRASAV as ATORVASTATIN CALCIUM TRIHYDRATE
  • AVSTAT as ATORVASTATIN CALCIUM TRIHYDRATE
  • CADITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • CHOVASTIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • CIDOVASTIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • FILSTATIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • MYOTEL as ATORVASTATIN CALCIUM TRIHYDRATE
  • STERTOVAS as ATORVASTATIN CALCIUM TRIHYDRATE
  • STORVAS as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) POLITOR PLUS as ATORVASTATIN CALCIUM TRIHYDRATE

Poland (PL)

  • ATORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORVAGEN as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORVASTEROL as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORVOX as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATOSTAT as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATRACTIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATROX as ATORVASTATIN CALCIUM TRIHYDRATE
  • CALIPRA as ATORVASTATIN CALCIUM TRIHYDRATE
  • CORATOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • LAMBRINEX as Atorvastatin calcium
  • LARUS as ATORVASTATIN CALCIUM TRIHYDRATE
  • OLVASTIM as ATORVASTATIN CALCIUM TRIHYDRATE
  • SORTIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • STORVAS as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVACARD as Atorvastatin calcium
  • TORVALIPIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • TULIP as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) AMLATOR as ATORVASTATIN LYSINE
  • (combination) AMLOSATIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) ATORDAPIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) EUVASCOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) MIZETAM as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) PARVAXOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TORVAZIN PLUS as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TRIVERAM as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TULIP COMBO as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) ZENTASTA as ATORVASTATIN CALCIUM TRIHYDRATE

Romania (RO)

  • AMICOR
  • ASCORD as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • SORTIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • STAVRA as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVACARD as Atorvastatin calcium

  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) COLEATEZ as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) DUPLECOR as ATORVASTATIN LYSINE
  • (combination) LIPERTANCE
  • (combination) TORVAZIN PLUS as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) ZETOVAR as ATORVASTATIN CALCIUM TRIHYDRATE

Singapore (SG)

  • ATAVOR as Atorvastatin calcium
  • ATOCOR as Atorvastatin calcium
  • ATORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATORSAN as Atorvastatin calcium
  • ATORVON as Atorvastatin calcium
  • ATSWIFT as ATORVASTATIN CALCIUM TRIHYDRATE
  • BEATORVA as ATORVASTATIN CALCIUM TRIHYDRATE
  • ETURION as ATORVASTATIN CALCIUM TRIHYDRATE
  • INATORVAS
  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVALIPIN as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVATEC as ATORVASTATIN CALCIUM TRIHYDRATE
  • TULIP as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TRINOMIA
  • (combination) TRIVERAM as ATORVASTATIN CALCIUM TRIHYDRATE

South Africa (ZA)

Spain (ES)

  • ATORIS as ATORVASTATIN CALCIUM TRIHYDRATE
  • CARDYL as ATORVASTATIN CALCIUM TRIHYDRATE
  • PREVENCOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • THERVAN as ATORVASTATIN CALCIUM TRIHYDRATE
  • ZARATOR as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ASTUCOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) ATOZET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) ORVATEZ as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TRINOMIA

Tunisia (TN)

Turkey (TR)

  • ALVASTIN as ATORVASTATIN CALCIUM ANHYDROUS
  • AMVASTAN as ATORVASTATIN CALCIUM TRIHYDRATE
  • ATEROZ as ATORVASTATIN CALCIUM TRIHYDRATE
  • AVITOREL as ATORVASTATIN CALCIUM TRIHYDRATE
  • AZIMBRA as ATORVASTATIN CALCIUM TRIHYDRATE
  • CARDYN as ATORVASTATIN CALCIUM TRIHYDRATE
  • CHOLVAST
  • COLASTIN-L as ATORVASTATIN CALCIUM TRIHYDRATE
  • DIVATOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • KOLESTOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPIDRA
  • LIPITAKSIN
  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE
  • LIPSUM
  • SAPHIRE as ATORVASTATIN CALCIUM TRIHYDRATE
  • TARDEN as ATORVASTATIN CALCIUM TRIHYDRATE
  • TORVAXAL as ATORVASTATIN CALCIUM TRIHYDRATE

  • (combination) ATODIP as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) ATOPIR as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) CADUET as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) EZETEC PLUS as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) FIXLIP as ATORVASTATIN CALCIUM TRIHYDRATE
  • (combination) TRATEZ as ATORVASTATIN CALCIUM TRIHYDRATE

United Kingdom (UK)

  • LIPITOR as ATORVASTATIN CALCIUM TRIHYDRATE

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

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