TRIVERAM

This brand name is authorized in Cyprus, Ecuador, Estonia, Finland, France, Lithuania, Poland, Singapore

Active ingredients

The drug TRIVERAM contains a combination of these active pharmaceutical ingredients (APIs):

1 Atorvastatin
UNII 48A5M73Z4Q - ATORVASTATIN CALCIUM TRIHYDRATE

Atorvastatin is a selective, competitive inhibitor of HMG-CoA reductase. Atorvastatin lowers plasma cholesterol and lipoprotein serum concentrations by inhibiting HMG-CoA reductase and subsequently cholesterol biosynthesis in the liver and increases the number of hepatic LDL receptors on the cell surface for enhanced uptake and catabolism of LDL.

Read about Atorvastatin
2 Perindopril
UNII TFT5IM1KGB - PERINDOPRIL ARGININE

Perindopril is an inhibitor of the enzyme that converts angiotensin I into angiotensin II (Angiotensin Converting Enzyme ACE). The converting enzyme, or kinase, is an exopeptidase that allows conversion of angiotensin I into the vasoconstrictor angiotensin II as well as causing the degradation of the vasodilator bradykinin into an inactive heptapeptide. Inhibition of ACE results in a reduction of angiotensin II in the plasma, which leads to increased plasma renin activity (by inhibition of the negative feedback of renin release) and reduced secretion of aldosterone. Since ACE inactivates bradykinin, inhibition of ACE also results in an increased activity of circulating and local kallikrein-kinin systems (and thus also activation of the prostaglandin system).

Read about Perindopril
3 Amlodipine
UNII 864V2Q084H - AMLODIPINE BESYLATE

Amlodipine is a calcium ion influx inhibitor of the dihydropyridine group (slow channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle.

Read about Amlodipine

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
TRIVERAM Film-coated tablet Health Sciences Authority (SG) MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
C10BX11 C Cardiovascular system → C10 Lipid modifying agents → C10B Lipid modifying agents, combinations → C10BX Lipid modifying agents in combination with other drugs
Discover more medicines within C10BX11

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: EC Agencia Nacional de Regulación, Control y Vigilancia Sanitaria Identifier(s): 4422-MEE-1018, 4436-MEE-1018, 4754-MEE-0619
Country: EE Ravimiamet Identifier(s): 1641585, 1641596, 1641608, 1641619, 1641620, 1641631, 1641642, 1641653, 1641664, 1641675, 1641686, 1641697, 1641709, 1641710, 1641721, 1722394, 1774548, 1774559, 1774571, 1774582, 1774593, 1774605, 1774616, 1774627, 1774638, 1774649
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 075959, 125705, 195850, 371287, 413892, 414769, 419445, 440335, 457193, 495828
Country: FR Base de données publique des médicaments Identifier(s): 62005075, 62557522, 65616495, 67767186, 69779664
Country: LT Valstybinė vaistų kontrolės tarnyba Identifier(s): 1072919, 1072920, 1072921, 1072922, 1072923, 1072924, 1072925, 1072926, 1072927, 1072928, 1078589, 1078590, 1078591, 1078592, 1078593, 1080458, 1085704, 1085705, 1085706, 1085707, 1085708, 1085709, 1085710, 1085711, 1085712, 1085713
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100351021, 100351044, 100351050, 100351067, 100351073
Country: SG Health Sciences Authority Identifier(s): 15426P, 15427P, 15428P, 15429P, 15430P

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