Amlodipine

Active ingredient description

Amlodipine is a calcium ion influx inhibitor of the dihydropyridine group (slow channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Amlodipine
C Cardiovascular system → C08 Calcium channel blockers → C08C Selective calcium channel blockers with mainly vascular effects → C08CA Dihydropyridine derivatives
Discover more medicines within C08CA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK
Structured Product Labeling (SPL/PLR)
US

Medicines

Amlodipine is the active ingredient of these drugs:

Drug
Countries

Italy

Hong Kong Singapore

Cyprus Hong Kong

Estonia Lithuania Poland

Poland

Brazil

Romania

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Poland

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Estonia Lithuania Poland

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Singapore South Africa

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Estonia Hong Kong Lithuania Poland

Brazil

Austria

Austria

Tunisia Turkey

Ecuador

Japan Tunisia

Turkey

Hong Kong

Turkey

Turkey

Poland

Hong Kong Singapore

Poland

Hong Kong Poland Singapore

Italy

Hong Kong South Africa

Ecuador France Tunisia

Finland

Cyprus Hong Kong

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Ireland

Hong Kong Singapore Tunisia

Hong Kong Turkey

Brazil Hong Kong

Ecuador

Poland

Hong Kong

Hong Kong

Hong Kong

Hong Kong Singapore South Africa

Mexico

Hong Kong

Brazil

Hong Kong Singapore

Brazil

Italy

South Africa

Spain

Singapore

Italy

Brazil

South Africa

Turkey

Cyprus

Tunisia

Poland

Ecuador

Turkey

Hong Kong

South Africa

Brazil

Poland

Turkey

Lithuania

Mexico

Poland

Turkey

Ecuador

Estonia

Hong Kong

Hong Kong

Hong Kong

Ireland United Kingdom

Ecuador

Hong Kong

United States

South Africa

South Africa

Italy

Tunisia

Tunisia

Singapore

Estonia Hong Kong

Hong Kong

South Africa

Hong Kong

Italy

Tunisia

Tunisia

Turkey

Italy

Brazil

Turkey

Ecuador

South Africa

Australia

Turkey

Ecuador

Hong Kong Singapore

Estonia Poland

Turkey

Turkey

Turkey

Australia

Mexico Spain

Australia Austria Brazil Canada Cyprus

South Africa

New Zealand

South Africa

Turkey

Italy

Brazil

Brazil

Hong Kong

Singapore

Singapore

Turkey

Brazil

Lithuania Poland Romania Singapore

Brazil

Tunisia

Hong Kong

Ecuador

Singapore

South Africa

South Africa

Ecuador

Turkey

New Zealand

Ecuador

Turkey

Poland

Spain

Hong Kong Singapore

Amlodipine is also found within below combination drugs:

ACERTANLO , ACERYCAL , ACROVASTIN AMLO , ALAMUT , ALBIS , ALBIS PLUS , ALENCAL VALS , ALORTIA , ALOTENDIN , AMALORIS , AMALUET , AMELIOR , AMELIOR PLUS , AMLATOR , AMLESSA , AMLESSINI , AMLIPIN , AMLONEB , AMLOPER , AMLOPRES , AMLOPRESS PLUS , AMLOSARTAN , AMLOSATIN , AMLOVALSAX , AMLOVAR , AMODUO , AMOLISA HCT , AMPLEX , AMRAP , AMSTADIN , AMTELIP , AMVADRAN , AMVALO , AMZAAR XQ , ANGIOTEN AMLO , APREXEVO , APROFORT , APROVASC , ARADEUX PLUS , ARAVEN IC , ARMIPIN , ARPEDON , ARPLEXAM , ASBIMA , ASTUCOR , ATODIP , ATORDAPIN , ATORVALAN COMP , AVASART PLUS , AVIRENA , AXELER , AZOR , AZOREN , BALZAK , BALZAK PLUS , BEATIL , BENICAR TRIPLO , BENICARANLO , BERALOSART XQ , BETALOR , BEVACOMB , BICARTIAL , BIPROCARD AMLO , BIRAMLO , BISOCOR AMLO , BISODIPIN , BISTENZID , BIVIS , BOTINERO , BRANTA , BRASART BCC , BRAVAN DUO , CADIVAST , CADUET , CALSAR , CAMDERO , CAMLOCOR , CAMLOSTAR , CAMSHIA , CANDAM , CANDEAMLO , CANDECAM , CANDECOR-AMLO , CANDETENS , CANDEZEK COMBI , CANLOX , CANLOX PLUS , CAPENON , CAPENON HCT , CARAMLO , CARDIK 3 , CARDIK A , CARDIOCAP A , CARDOFIX , CARDOFIX PLUS , CENART , CENART PLUS , CO EXFORGE , CO-AMLESSA , CO-DALNESSA , CO-PRESTARIUM , CO-THERAPRIL , CODUWON , COMBISAR , COMBISAR PLUS , CONCOR AM , CONCOR AMLO , CONCOR ANLO , CONCORAM , CONSENSI , CONVERTAL PLUS , COPALIA , COPALIA HCT , CORAZOX AMLO , COREYRA , COSARTAN ALP , COVERAM , COVERDINE , COVERLAM , COZAAR XQ , DAFIRO , DAFIRO HCT , DALNESSA , DALNEVA , DIOVAN AMLO FIX , DIPPERAM , DIPPERAM HCT , DIPPVOL , DIRONORM , DISARTEC , DUOALMETEC , DUOFOR , DUOFOR PLUS , DUOTENS , DUOTRESTAR , DUPLECOR , EGIRAMLON , ELESTAR , ELESTAR HCT , EUROCOR AM , EXCALIBA , EXCALIBA PLUS , EXFORGE , EXFORGE HCT , FINAXTRIL , FIXIT , FIXIT H , FLAMIPAX , FLUDEXAM , FLUTENSIF , FLUXOCOR ANLO , FRAMSYL , GADUAR , GEMVALAZ , HIFORGE , HIPOVAS , ICATENS , ICOMB , ILTUXAM , ILUAMIX , IMLO , IMPRIDA , INOVUM , INOVUM HCT , IRBEAM , IRDAPIN , IRDAPIN PLUS , KANDOSET , KARVEA DUO , KONVERGE , KONVERGE PLUS , LIPERTANCE , LIPTA , LISAM , LODICAND , LODITEN , LOPRIDAM , LOSAMLO , LOTAR , LOTREL , MAXOPRESS , MICAMLO , MICARDIS AMLO , MICARDIS ANLO , MICARDIS DUO , MIDAX AM , MINART AM , MIXANVAL , MIXOR , NAPRIX A , NATRIXAM , NEAFORGE , NORMOTRI , NORPLEXAM , NORVAN , NORVASTOR , OLMECOMB , OLMECOMB PLUS , OLMEDIPIN , OLMEKAR , OLMEKAR HCT , OLMETECANLO , OLMIRA , OLMITA , OLMY ANLO , OLMYSAR COMBO , OLMYSAR TRIO , OLSITRI , OLSSA , ORIZAL , ORIZAL PLUS , PARVATI , PEMTORI , PERAM , PERTENA AM , PERTENA COMPLETE , PREAMLESSA , PREMINOR , PRESS PLUS , PRESTALIA , PRESTANCE , PRESTERAM , PRESTOZEK COMBI , PRESUCOMB , PRIAMLO , PRINDAL , PRYLAR , RACORVAL A , RAMANTAL , RAMDACORDIA , RAMDACORDIA HCT , RAMEAM , RAMI-AMLO , RAMIDIPIN , RAMIZEK COMBI , RAMLADIO , RAMLON , RASERTAN PLUS , RASILAMLO , RAVENTON , REAPTAN , RETILCOMB , REVERANTZA , RIMAL , ROSAMERA , ROSUCOR PLUS , ROSUDAPIN , ROSULOD , ROSVADEN , ROXAMPEX , ROZAMLAD , SALVO , SAMBETAN , SANORAL , SANORAL HCT , SARPIN , SARTABE AM , SARTESTA , SEVIKAR , SEVIKAR HCT , SEVIKAR PLUS , SIMULTAN A , SIMULTAN TRIPLE , SINERGEN , SOBYCOMBI , SUB-ZERO , SUMILAR , SUMILAR HCT , TAKAWITA , TANSIFA , TANSIFA PLUS , TELAM , TELASSMO , TELDIPIN , TELMODIP , TELMODIP PLUS , TELSAR AM , TENLORIS , TENSIOVALS DUO , TENSIUM AM , TERAMURO , TERTENS-AM , TILAMCAR , TONARSSA , TONOTEC , TRIAMLO , TRIBENZOR , TRIPLIAM , TRIPLIXAM , TRITAMLO , TRIVERAM , TWYNSTA , UNISIA , VALAFOR , VALAXAM , VALAXAM D , VALCARDIO A , VALCARDIO PLUS , VALCODIN , VALDIPIN , VALDUO , VALGAMEZ , VALSAM , VALSAMIX , VALSIMIA , VALTAN-A , VALTRICOM , VALUE PLUS , VALVASC , VARTERAL , VARTERAL HCT , VASDAY , VIACORAM , VIACORLIX , VIDONORM , VILPIN COMBI , VOCADO , WAMLOX , ZAHRON COMBI , ZENICAMO , ZILMLO

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₀H₂₅ClN₂O₅
Molecular mass: 408.876 g/mol

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 88150-42-9
DrugBank Drug: DB00381
KEGG Drug: D07450
PubChem Compound: 2162
RxNorm Ingredient: 17767
SNOMED-CT Concept: 386864001
Amlodipine (substance)
UNII Identifier: 1J444QC288
AMLODIPINE