APREXEVO

This brand name is authorized in Romania

Active ingredients

The drug APREXEVO contains a combination of these active pharmaceutical ingredients (APIs):

1 Irbesartan
UNII J0E2756Z7N - IRBESARTAN

Irbesartan is a potent, orally active, selective angiotensin-II receptor (type AT1) antagonist. It is expected to block all actions of angiotensin-II mediated by the AT1 receptor, regardless of the source or route of synthesis of angiotensin-II. The selective antagonism of the angiotensin-II (AT1) receptors results in increases in plasma renin levels and angiotensin-II levels, and a decrease in plasma aldosterone concentration.

Read about Irbesartan
2 Amlodipine
UNII 864V2Q084H - AMLODIPINE BESYLATE

Amlodipine is a calcium ion influx inhibitor of the dihydropyridine group (slow channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle.

Read about Amlodipine

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
C09DB05 Irbesartan and amlodipine C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09D Angiotensin II antagonists, combinations → C09DB Angiotensin II antagonists and calcium channel blockers
Discover more medicines within C09DB05

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale Identifier(s): W66856001, W66856002, W66856003, W66856004, W66856005, W66857001, W66857002, W66857003, W66857004, W66857005, W66858001, W66858002, W66858003, W66858004, W66858005, W66859001, W66859002, W66859003, W66859004, W66859005

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