APROVASC

This brand name is authorized in Ecuador, Mexico, Tunisia, South Africa

Active ingredients

The drug APROVASC contains a combination of these active pharmaceutical ingredients (APIs):

1 Irbesartan
UNII J0E2756Z7N - IRBESARTAN

Irbesartan is a potent, orally active, selective angiotensin-II receptor (type AT1) antagonist. It is expected to block all actions of angiotensin-II mediated by the AT1 receptor, regardless of the source or route of synthesis of angiotensin-II. The selective antagonism of the angiotensin-II (AT1) receptors results in increases in plasma renin levels and angiotensin-II levels, and a decrease in plasma aldosterone concentration.

Read about Irbesartan
2 Amlodipine
UNII 864V2Q084H - AMLODIPINE BESYLATE

Amlodipine is a calcium ion influx inhibitor of the dihydropyridine group (slow channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle.

Read about Amlodipine

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
APROVASC Film-coated tablet Marketing Authorisation Holder MPI, Generic

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
C09DB05 Irbesartan and amlodipine C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09D Angiotensin II antagonists, combinations → C09DB Angiotensin II antagonists and calcium channel blockers
Discover more medicines within C09DB05

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: EC Agencia Nacional de Regulación, Control y Vigilancia Sanitaria Identifier(s): 363091112, 363161112, 363301112
Country: MX Comisión Federal para la Protección contra Riesgos Sanitarios Identifier(s): 180M2011
Country: TN Direction de la Pharmacie et du Médicament Identifier(s): 9263261, 9263262, 9263263
Country: ZA Health Products Regulatory Authority Identifier(s): 46/7.1.3/0542, 46/7.1.3/0543, 46/7.1.3/0544, 46/7.1.3/0545

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