Post lumbar puncture headache

Active Ingredient: Desmopressin

Indication for Desmopressin

Population group: only adults (18 - 65 years old)
Therapeutic intent: Curative procedure

For this indication, competent medicine agencies globally authorize below treatments:

4 ug once

For:

Dosage regimens

Regimen A: Subcutaneous, 4 micrograms desmopressin, once daily, 1 to 2 doses in total.

Regimen B: Intramuscular, 4 micrograms desmopressin, once daily, 1 to 2 doses in total.

Detailed description

Where a headache is thought to be due to a lumbar puncture, an adult patient can be given a dose of 4 micrograms desmopressin injection which may be repeated 24 hours later if necessary.

Active ingredient

Desmopressin

Desmopressin is a structural analogue of vasopressin in which the antidiuretic activity has been enhanced by the order of 10, while the vasopressor effect has been reduced by the order of 1500. The clinical advantage of this highly changed ratio of antidiuretic to vasopressor effect is that clinically active antidiuretic doses are far below the threshold for a vasopressor effect.

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