Chemical formula: C₄₆H₆₄N₁₄O₁₂S₂ Molecular mass: 1,069.22 g/mol
Desmopressin is a structural analogue of vasopressin in which the antidiuretic activity has been enhanced by the order of 10, while the vasopressor effect has been reduced by the order of 1500. The clinical advantage of this highly changed ratio of antidiuretic to vasopressor effect is that clinically active antidiuretic doses are far below the threshold for a vasopressor effect.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| H01BA02 | Desmopressin | H Systemic hormonal preparations, excl. Sex hormones and insulins → H01 Pituitary and hypothalamic hormones and analogues → H01B Posterior pituitary lobe hormones → H01BA Vasopressin and analogues |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| DDAVP MELT Oral lyophilisate | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| DESMOTABS Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| DESMOPRESSIN Nasal spray, solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| OCTOSTIM Solution for injection | Health Products and Food Branch (CA) | MPI, CA: SPM | |
| DDAVP DESMOPRESSIN Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Desmopressin is an active ingredient of these brands:
Australia (AU)
Austria (AT)Brazil (BR)
Canada (CA)Cyprus (CY)
Ecuador (EC)Estonia (EE)Finland (FI)Hong Kong (HK)Ireland (IE)
Japan (JP)
Lithuania (LT)Mexico (MX)
Netherlands (NL)Nigeria (NG)
Poland (PL)Singapore (SG)South Africa (ZA)Spain (ES)Tunisia (TN)
Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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