Gynaecological infections

Active Ingredient: Aztreonam

Indication for Aztreonam

Population group: women, only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

2-8 g in 2-4 divided doses daily

Route of admnistration

Intravenous

Defined daily dose

2 - 8 g

Dosage regimen

From 0.5 To 2 g 4 time(s) per day every day

Detailed description

Moderately severe systemic infections: 1 g or 2 g every 8 or 12 hours.

Severe systemic or life-threatening infections: 2 g every 6 or 8 hours.

Dosage considerations

For intravenous injection

To the contents of the vial add 6 to 10 mL of Water for Injections Ph. Eur. and shake well. Slowly inject directly into the vein over a period of 3 to 5 minutes.

For intravenous infusion:

Vials: For each gram of aztreonam add at least 3 mL of Water for Injections Ph. Eur. and shake well.

Dilute this initial solution with an appropriate infusion solution to a final concentration less than 2% w/v (at least 50 mL solution per gram of aztreonam). The infusion should be administered over 20-60 minutes.

2-8 g in 2-4 divided doses daily

Route of admnistration

Intramuscular

Defined daily dose

2 - 8 g

Dosage regimen

From 0.5 To 2 g 4 time(s) per day every day

Detailed description

Moderately severe systemic infections: 1 g or 2 g every 8 or 12 hours.

Severe systemic or life-threatening infections: 2 g every 6 or 8 hours.

Dosage considerations

For intravenous injection

To the contents of the vial add 6 to 10 mL of Water for Injections Ph. Eur. and shake well. Slowly inject directly into the vein over a period of 3 to 5 minutes.

For intravenous infusion:

Vials: For each gram of aztreonam add at least 3 mL of Water for Injections Ph. Eur. and shake well.

Dilute this initial solution with an appropriate infusion solution to a final concentration less than 2% w/v (at least 50 mL solution per gram of aztreonam). The infusion should be administered over 20-60 minutes.

Active ingredient

Aztreonam

Aztreonam exhibits activity in vitro against gram-negative aerobic pathogens, including P. aeruginosa. Aztreonam binds to penicillin-binding proteins of susceptible bacteria, which leads to inhibition of bacterial cell wall synthesis, followed by filamentation and cell lysis.

Read more about Aztreonam

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner

Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.