Aztreonam

Chemical formula: C₁₃H₁₇N₅O₈S₂  Molecular mass: 435.433 g/mol  PubChem compound: 5742832

Active ingredient description

Aztreonam exhibits activity in vitro against gram-negative aerobic pathogens, including P. aeruginosa. Aztreonam binds to penicillin-binding proteins of susceptible bacteria, which leads to inhibition of bacterial cell wall synthesis, followed by filamentation and cell lysis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
J01DF01 Aztreonam J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01D Other beta-lactam antibacterials → J01DF Monobactams
Discover more medicines within J01DF01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 AZACTAM Powder for solution for injection or infusion MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 CAYSTON Powder and solvent for nebuliser solution MPI, EU: SmPC European Medicines Agency (EU)

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 78110-38-0
DrugBank Drug: DB00355
KEGG Drug: D00240
PubChem Compound: 5742832
RxNorm Ingredient: 1272
SNOMED-CT Concept: 387386004
Aztreonam (substance)
UNII Identifier: G2B4VE5GH8
AZTREONAM

Medicines

Aztreonam is an active ingredient of these brands:

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Malta (MT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Singapore (SG)

Spain (ES)

United Kingdom (UK)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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