Aztreonam

Chemical formula: C₁₃H₁₇N₅O₈S₂  Molecular mass: 435.433 g/mol  PubChem compound: 5742832

Active ingredient description

Aztreonam exhibits activity in vitro against gram-negative aerobic pathogens, including P. aeruginosa. Aztreonam binds to penicillin-binding proteins of susceptible bacteria, which leads to inhibition of bacterial cell wall synthesis, followed by filamentation and cell lysis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
J01DF01
Aztreonam
J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01D Other beta-lactam antibacterials → J01DF Monobactams
Discover more medicines within J01DF01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
AZACTAM Powder for solution for injection or infusion
Medicines & Healthcare Products Regulatory Agency (GB)
MPI, EU: SmPC
CAYSTON Powder and solvent for nebuliser solution
European Medicines Agency (EU)
MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 78110-38-0
DrugBank Drug: DB00355
KEGG Drug: D00240
PubChem Compound: 5742832
RxNorm Ingredient: 1272
SNOMED-CT Concept: 387386004
Aztreonam (substance)
UNII Identifier: G2B4VE5GH8
AZTREONAM

Medicines

Aztreonam is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Canada (CA)

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Malta (MT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Singapore (SG)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
Next: Usage >

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.

⇈