Reflux oesophagitis

Active Ingredient: Omeprazole

Indication for Omeprazole

Population group: only adults (18 years old or older)

Treatment of reflux oesophagitis.

For this indication, competent medicine agencies globally authorize below treatments:

20-40 mg once daily

Route of admnistration

Oral

Defined daily dose

10 - 40 mg

Dosage regimen

From 10 To 40 mg once every day

Loading dose

20 mg

Detailed description

The recommended dose is omeprazole 20mg once daily. In most patients healing occurs within four weeks. For those patients who may not be fully healed after the initial course, healing usually occurs during a further four weeks treatment period.

In patients with severe oesophagitis omeprazole 40mg once daily is recommended and healing is usually achieved within eight weeks.

Long-term management of patients with healed reflux oesophagitis

For the long-term management of patients with healed reflux oesophagitis the recommended dose is omeprazole 10mg once daily. If needed, the dose can be increased to omeprazole 20-40mg once daily.

Dosage considerations

It should be taken in the morning.

40 mg once daily

Route of admnistration

Intravenous

Defined daily dose

40 - 40 mg

Dosage regimen

From 40 To 40 mg once every day

Loading dose

40 mg

Maintenance dose

40 mg

Detailed description

In patients where the use of oral medicinal products is inappropriate, omeprazole IV 40 mg once daily is recommended.

Dosage considerations

Omeprazole is to be administered in an intravenous infusion for 20-30 minutes.

Active ingredient

Omeprazole

Omeprazole, a racemic mixture of two enantiomers reduces gastric acid secretion through a highly targeted mechanism of action. It is a specific inhibitor of the acid pump in the parietal cell. It is rapidly acting and provides control through reversible inhibition of gastric acid secretion with once daily dosing.

Read more about Omeprazole

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