Active Ingredient: Insulin lispro
For the treatment of adults and children with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis. Insulin lispro is also indicated for the initial stabilisation of diabetes mellitus.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Subcutaneous, between 0.3 arbitary units insulin lispro and 1 arbitary units insulin lispro, divided 3 times daily.
Insulin lispro may be given shortly before meals. When necessary insulin lispro can be given soon after meals.
Insulin lispro takes effect rapidly and has a shorter duration of activity (2 to 5 hours) given subcutaneously as compared with soluble insulin. This rapid onset of activity allows a insulin lispro injection (or, in the case of administration by continuous subcutaneous infusion, a insulin lispro bolus) to be given very close to mealtime. The time course of action of any insulin may vary considerably in different individuals or at different times in the same individual. The faster onset of action compared to soluble human insulin is maintained regardless of injection site. As with all insulin preparations, the duration of action of insulin lispro is dependent on dose, site of injection, blood supply, temperature, and physical activity.
Insulin lispro can be used in conjunction with a longer-acting insulin or oral sulphonylurea agents, on the advice of a physician.
Subcutaneous administration should be in the upper arms, thighs, buttocks, or abdomen. Use of injection sites should be rotated so that the same site is not used more than approximately once a month.
When administered subcutaneously care should be taken when injecting Humalog to ensure that a blood vessel has not been entered. After injection, the site of injection should not be massaged. Patients must be educated to use the proper injection techniques.
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