Primary nocturnal enuresis

Indication for Desmopressin

Population group: Suitable for both men and women, only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 - 65 years old)
Therapeutic intent: Curative procedure

For this indication, competent medicine agencies globally authorize below treatments:

120-240 ug once daily

For: Children Adolescents Adults (18-64)

Dosage regimens

Sublingual, between 120 and 240 micrograms, once daily at the end of the day, over the duration of 3 months.

200-400 ug once daily

For: Children Adolescents Adults (18-64) Elders (65+)

Dosage regimens

Solution oral, between 180 and 360 micrograms, once daily at the end of the day, over the duration of 3 months.

Detailed description

Children (from 5 years of age) and adults (up to 65 years of age) with normal urine concentrating ability who have primary nocturnal enuresis should take 0.2mg at bedtime and only if needed should the dose be increased to 0.4mg.

The need for continued treatment should be reassessed after 3 months by means of a period of at least 1 week without desmopressin tablets.

0.2-0.4mg once daily

For: Children Adolescents Adults (18-64)

Dosage regimens

Tablet oral, between 0.2 and 0.4 milligrams, once daily at the end of the day, over the duration of 3 months.

Detailed description

Children (from 5 years of age) and adults (up to 65 years of age) with normal urine concentrating ability who have primary nocturnal enuresis should take 0.2mg at bedtime and only if needed should the dose be increased to 0.4mg.

The need for continued treatment should be reassessed after 3 months by means of a period of at least 1 week without desmopressin tablets.

Active ingredient

Desmopressin is a structural analogue of vasopressin in which the antidiuretic activity has been enhanced by the order of 10, while the vasopressor effect has been reduced by the order of 1500. The clinical advantage of this highly changed ratio of antidiuretic to vasopressor effect is that clinically active antidiuretic doses are far below the threshold for a vasopressor effect.

Read more about Desmopressin

Related medicines

Develop a tailored medication plan for your case, considering factors such as age, gender, and health history

Ask the Reasoner