For this indication, competent medicine agencies globally authorize below treatments:
Intramuscular
3.75 - 3.75 mg
From 3.75 To 3.75 mg once every 30 day(s)
The usual recommended dose of leuprorelin is 3.75 mg presented as a one month depot injection and administered as a single intramuscular injection every month.
Leuprorelin must be administered under the supervision of a physician or a qualified health practitioner.
The dose of leuprorelin allowing the continuous release of leuprorelin acetate during one month is incorporated in a depot formulation. The lyophilized powder should be reconstituted and administered as a single intramuscular injection at monthly intervals. Intra-arterial or intravenous administration must be avoided. The vial of leuprorelin microsphere powder should be reconstituted immediately prior to administration by intramuscular injection. As with other drugs administered regularly by injection, the injection site should be varied periodically.
Leuprorelin therapy should not be discontinued when remission or improvement occurs.
Response to leuprorelin therapy should be monitored measuring serum levels of testosterone as well as prostate-specific antigen (PSA) periodically.
If a patient’s response appears to be sub-optimal, then it would be advisable to confirm that serum testosterone levels have reached or are remaining at castrate levels. Transient increases in acid phosphatase levels sometimes occur early in the treatment period but usually return to normal or near normal values by the 4th week of treatment.
Duration of treatment: Leuprorelin should be administered as monthly intramuscular injections. As a rule, prostate cancer therapy with leuprorelin entails long-term treatment and therapy should not be discontinued when remission or improvement occurs.
Subcutaneous
3.75 - 3.75 mg
From 3.75 To 3.75 mg once every 30 day(s)
Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.