Diabetes mellitus

Active Ingredient: Insulin (human)

Indication for Insulin (human)

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Insulin is indicated for treatment of diabetes mellitus.

For this indication, competent medicine agencies globally authorize below treatments:

0.3-1.0 IU/kg in 3 divided doses daily

Route of admnistration

Subcutaneous

Defined daily dose

0.3 - 1 [iU] per kg of body weight

Dosage regimen

From 0.1 To 0.333 [iU] per kg of body weight 3 time(s) per day every day

Detailed description

The potency of human insulin is expressed in international units.

Insulin dosing is individual and determined in accordance with the needs of the patient. It can be used alone or in combination with intermediate-acting or long-acting insulin before a meal or a snack.

The individual insulin requirement is usually between 0.3 and 1.0 international unit/kg/day. Adjustment of dose may be necessary if patients undertake increased physical activity, change their usual diet or during concomitant illness.

Dosage considerations

Insulin is administered subcutaneously by injection in the abdominal wall, the thigh, the gluteal region or the deltoid region. Injection into a lifted skin fold minimises the risk of unintended intramuscular injection.

The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected. Injection sites should always be rotated within the same region in order to reduce the risk of lipodystrophy. Subcutaneous injection into the abdominal wall ensures a faster absorption than other injection sites. The duration of action will vary according to the dose, injection site, blood flow, temperature and level of physical activity.

An injection should be followed within 30 minutes by a meal or snack containing carbohydrates.

0.3-1.0 IU/kg in 3 divided doses daily

Route of admnistration

Intravenous

Defined daily dose

0.3 - 1 [iU] per kg of body weight

Dosage regimen

From 0.1 To 0.333 [iU] per kg of body weight 3 time(s) per day every day

Detailed description

The potency of human insulin is expressed in international units.

Actrapid dosing is individual and determined in accordance with the needs of the patient. It can be used alone or in combination with intermediate-acting or long-acting insulin before a meal or a snack.

The individual insulin requirement is usually between 0.3 and 1.0 international unit/kg/day. Adjustment of dose may be necessary if patients undertake increased physical activity, change their usual diet or during concomitant illness.

Dosage considerations

Insulin is administered subcutaneously by injection in the abdominal wall, the thigh, the gluteal region or the deltoid region. Injection into a lifted skin fold minimises the risk of unintended intramuscular injection.

The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected. Injection sites should always be rotated within the same region in order to reduce the risk of lipodystrophy. Subcutaneous injection into the abdominal wall ensures a faster absorption than other injection sites. The duration of action will vary according to the dose, injection site, blood flow, temperature and level of physical activity.

An injection should be followed within 30 minutes by a meal or snack containing carbohydrates.

Active ingredient

Insulin (human)

The blood glucose lowering effect of insulin is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

Read more about Insulin (human)

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