Chemical formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆ Molecular mass: 5,805.644 g/mol
The blood glucose lowering effect of insulin is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A10AB01 | Insulin (human) | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AB Insulins and analogues for injection, fast-acting |
| A10AC01 | Insulin (human) | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AC Insulins and analogues for injection, intermediate-acting |
| A10AD01 | Insulin (human) | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AD Insulins and analogues for injection, intermediate-acting combined with fast-acting |
| A10AE01 | Insulin (human) | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AE Insulins and analogues for injection, long-acting |
| A10AF01 | Insulin (human) | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AF Insulins and analogues for inhalation |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ACTRAPID Solution for injection | European Medicines Agency (EU) | MPI, EU: SmPC | |
| HUMULIN I Suspension for injection in a vial | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Insulin (human) is an active ingredient of these brands:
Australia (AU)
Austria (AT)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Italy (IT)
Lithuania (LT)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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