Insulin (human)

Chemical formula: C₂₅₇H₃₈₃N₆₅O₇₇S₆  Molecular mass: 5,805.644 g/mol 

Active ingredient description

The blood glucose lowering effect of insulin is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A10AB01 Insulin (human) A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AB Insulins and analogues for injection, fast-acting
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A10AC01 Insulin (human) A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AC Insulins and analogues for injection, intermediate-acting
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A10AD01 Insulin (human) A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AD Insulins and analogues for injection, intermediate-acting combined with fast-acting
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A10AE01 Insulin (human) A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AE Insulins and analogues for injection, long-acting
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A10AF01 Insulin (human) A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10A Insulins and analogues → A10AF Insulins and analogues for inhalation
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Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
HUMULIN I Suspension for injection in a vial Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ACTRAPID Solution for injection European Medicines Agency (EU) MPI, EU: SmPC

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 11061-68-0
DrugBank Drug: DB00030
KEGG Drug: D03230
RxNorm Ingredient: 253182
UNII Identifier: 1Y17CTI5SR
INSULIN HUMAN

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