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ATC Group: A10AE Insulins and analogues for injection, long-acting

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
A
Alimentary tract and metabolism
2
A10
Drugs used in diabetes
3
A10A
Insulins and analogues
4
A10AE
Insulins and analogues for injection, long-acting

Contents

Code
Title
A10AE01
Insulin (human)
A10AE02
Insulin (beef)
A10AE03
Insulin (pork)
A10AE04
Insulin glargine
A10AE05
Insulin detemir
A10AE06
Insulin degludec
A10AE30
Combinations
A10AE54
Insulin glargine and lixisenatide
A10AE56
Insulin degludec and liraglutide

Active Ingredients

Chemical substance
Description
Insulin (human)

The blood glucose lowering effect of insulin is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

Insulin (pork)
Insulin degludec

Insulin degludec binds specifically to the human insulin receptor and results in the same pharmacological effects as human insulin. The blood glucose-lowering effect of insulin is due to the facilitated uptake of glucose following the binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.

Insulin detemir

Insulin detemir is a soluble, long-acting insulin analogue with a prolonged duration of effect used as a basal insulin.

Insulin glargine

Insulin glargine is a human insulin analogue designed to have a low solubility at neutral pH. After injection, the acidic solution is neutralised leading to formation of a precipitate from which small amounts of insulin glargine are continuously released.

Monographs

Monograph
Type
Country
BASAGLAR Solution for injection Kwikpen / Tempo pen
MPI, US: SPL/PLR
US
LEVEMIR Solution for injection
MPI, EU: SmPC
TOUJEO Solution for injection
MPI, EU: SmPC
TRESIBA Solution for injection
MPI, EU: SmPC